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CD8, Mouse Anti-Human
| Catalogue Number | ANT-148 | |||||
| Synonyms | CD8, MAL, p32. | |||||
| Type | Mouse Anti Human Monoclonal. | |||||
| Introduction | CD8 is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 acts as a co-receptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional CD8 is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8 identifies cytotoxic/suppressor t-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of t-cell mediated killing. CD8 alpha chains binds to class-I MHC molecules alpha-3 domains. | |||||
| Clone | hCD8. | |||||
| Immunogen | Purified human PBL CD8+ T cells. | |||||
| Ig Subclass | Mouse IgG2a. | |||||
| Purification Method | Ion exchange column. | |||||
| Protein concentration | 1mg/ml in PBS (after reconstitution). | |||||
| Storage Procedures | Lyophilized: store at 4oC. After reconstitution, if not intended for use within a month, aliquot and store at -20oC. | |||||
| Reconstitution | Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. | |||||
| Antibody Properties | Blocking and staining antibody. For staining, use 10µl/1,000,000 cells. Titer for blocking T cell activation should be determined by the investigator. | |||||
| Available Conjugates | This antibody is also available conjugated to biotin and FITC. For staining with biotin or FITC-conjugated antibody use 5-10µl/106 cells. | |||||
| Usage | Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. | |||||
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KRT23 ant-081 Mouse Anti Human Cytokeratin 23
LAIR1 ant-301 Mouse Anti Human Leukocyte-Associated Ig-Like Receptor 1
LY6C/G ant-075 Rat Anti Mouse LY6C/G
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LY6C/G FITC ant-076 Rat Anti Mouse LY6C/G FITC
LY6G ant-158 Rat Anti Mouse LY6G
LY6G Biotin ant-074 Rat Anti Mouse LY6G Biotin
LY6G FITC ant-099 Rat Anti Mouse LY6G FITC
MBP ant-177 Mouse Anti Maltose-Binding protein
MBP ant-451 Mouse Anti Maltose-Binding protein
MHC Class I ant-176 Mouse Anti MHC Class I (H-2K)
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MHC Class II ant-268 Mouse Anti MHC Class II (I-A)
MHC Class II ant-296 Mouse Anti Human MHC Class II
MHC Class II (I-E) ant-297 Mouse Anti MHC Class II (I-E)
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NFATC1 ant-436 Mouse Anti Human Nuclear factor of activated T-cells cytoplasmic 1
NKp30 ant-402 Mouse Anti Human Natural killer cell p30-related protein
NKp44 ant-401 Mouse Anti Human Natural killer cell p44-related protein
NKp46 ant-303 Mouse Anti Human Natural Cytotoxicity Receptor NKp46
NRAS ant-047 Mouse Anti Human Neuroblastoma RAS Viral Oncogene Homolog
OAT ant-013 Mouse Anti Human Ornithine aminotransferase
p53 ant-192 Recombinant Anti p53 scFv
p53 ant-228 Mouse Anti p53
PAP-1 ant-218 Polyclonal Rabbit Anti Human Pancreatitis-associated protein
PARK7 ant-317 Mouse Anti Human Parkinson Disease Protein 7
PCNA ant-341 Mouse Anti Human Proliferating Cell Nuclear Antigen
PDCD1 ant-417 Mouse Anti Human Programmed Cell Death 1
PDCD12 ant-457 Mouse Anti Human Programmed Cell Death 12
PDCD4 ant-338 Mouse Anti Human Programmed Cell Death 4
PDPN ant-343 Mouse Anti Human Podoplanin
PDX-1 ant-162 Polyclonal Rabbit Anti Pancreas Duodenum Homeobox-1
PGP9.5 ant-335 Mouse Anti Human PGP9.5
PLP ant-200 Mouse Anti Porteolipid Protein of Myelin
PSMA ant-450 Mouse Anti Human Prostate Specific Cancer Antigen
RAB5A ant-337 Mouse Anti Human RAB5A
Rac2 ant-067 Mouse Anti Human Ras-Related C3 Botulinum Toxin Substrate 2
RASSF1A ant-400 Mouse Anti Human Ras association domain-containing protein 1
REXO1 ant-413 Mouse Anti Human RNA exonuclease 1 homolog
SERPINB5 ant-364 Mouse Anti Human Serpin Peptidase Inhibitor, Clade B Member 5
SNAP25 ant-336 Mouse Anti Human Synaptosomal-associated protein 25
SNCA ant-315 Mouse Anti Human Alpha-Synuclein
SNCB ant-454 Polyclonal Rabbit Anti Human Beta-Synuclein
SNCG ant-455 Polyclonal Rabbit Anti Human Gamma-Synuclein
Streptavidin ant-345 Mouse Anti Streptavidin
SUMO2/3 ant-016 Mouse Anti Human Small Ubiquitin-Related Modifier 2/3
TARDBP ant-420 Mouse Anti Human TAR DNA-binding protein 43
TBCA ant-362 Mouse Anti Human Tubulin Folding Cofactor A
Tetanus ant-195 Recombinant Anti-Tetanus Toxoid scFv
TGFBI ant-349 Mouse Anti Human Transforming Growth Factor Beta Induced
TLR2 ant-408 Mouse Anti Human Toll-like receptor 2
TLR7 ant-403 Mouse Anti Human Toll-like receptor 7
TMEFF2 ant-428 Mouse Anti Human Tomoregulin-2
TOLLIP ant-430 Mouse Anti Human Toll-interacting protein
TPD52L1 ant-302 Mouse Anti Human Tumor Protein D52 L1
TREM2 ant-429 Mouse Anti Human Triggering receptor expressed on myeloid cells 2
TTR ant-003 Mouse Anti Human Transthyretin
TUBB2b ant-019 Mouse Anti Human Tubulin beta-2B chain
VAMP2 ant-334 Mouse Anti Human Synaptobrevin-2
VAMP3 ant-352 Mouse Anti Human Synaptobrevin-3
VHL ant-316 Mouse Anti Human Von Hippel-Lindau Protein
Vimentin ant-245 Mouse Anti Human Vimentin
Vimentin Biotin ant-246 Mouse Anti Human Vimentin Biotinylated
Vimentin FITC ant-247 Mouse Anti Human Vimentin FITC
WNT3A ant-431 Mouse Anti Human Protein Wnt-3a
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